Critique notes 83

The first 83 and the next 83: perspectives on neurotoxicology.

This commentary depicts the author's history, and how it became interwoven with neurotoxicology. Born in 1925, most of his life spanned a century burdened with calamitous wars as well as revolutionary developments in science. Aviation played a large role in the century's wars and in the author's outlook on the world. He moved from a literary perspective, after his war experiences, to one govern...

The Concept of Laws in Social Science: A Critique and Notes on an Expanded View

Agnostic Notes on Regression Adjustments to Experimental Data: Reexamining Freedman’s Critique By

Freedman [Adv. in Appl. Math. 40 (2008) 180–193; Ann. Appl. Stat. 2 (2008) 176–196] critiqued ordinary least squares regression adjustment of estimated treatment effects in randomized experiments, using Neyman’s model for randomization inference. Contrary to conventional wisdom, he argued that adjustment can lead to worsened asymptotic precision, invalid measures of precision, and small-sample ...

The Creature Before the Law: Notes on Walter Benjamin’s Critique of Violence

Transforming as it does from an exemplar of meticulous philosophical analysis into an allusive political/messianic tract, Walter Benjamin’s “Critique of Violence” is representative of all that is most difficult about his work. Against those critics who find the eschatological dimensions of Benjamin’s texts unpalatable and/or philosophically bankrupt, however, the wager of this paper is that it ...

Dmd066720 83..101

Regulatory approval documents contain valuable information, often not published, to assess the drug–drug interaction (DDI) profile of newly marketed drugs. This analysis aimed to systematically review all drug metabolism, transport, pharmacokinetics, and DDI data available in the new drug applications and biologic license applications approved by the U.S. Food and Drug Administration in 2014, u...